root canal education - patient friendly

Why Antibiotics Alone Rarely Fix a Root Canal Problem

Antibiotics can reduce toothache for a few days, but they cannot reach inside an infected nerve. In this guide, Dr Majid explains why pain often returns after antibiotics, when they help, and what actually treats the underlying infection inside the tooth.

Why antibiotics can feel like they “fixed” the tooth

When a tooth flares up, it is very tempting to hope that a course of antibiotics will solve the problem completely. Many patients tell me that the pain eased while they were taking tablets and they felt almost back to normal for a few days.

This happens because antibiotics can reduce the number of bacteria in the tissues around the tooth. They may calm the swelling in the gum or bone, lower the pressure and make it easier to sleep or chew for a short time.

The part antibiotics can reach

Antibiotics travel through your bloodstream. They can reach:

✔ The tissues around the root – such as the bone and ligament
✔ Areas where infection has spread beyond the tip of the root

This is why you may feel less throbbing or see swelling go down while you are on the medication. It can be a very welcome relief, especially if the pain was keeping you awake.

The part they cannot reach

Inside the centre of the tooth, the nerve space has little or no blood supply once it is badly inflamed or has died. Because antibiotics rely on blood flow to reach an area, they cannot properly get into that closed space to remove the source of infection.

How I explain it to patients

Antibiotics can help calm the area around the tooth, but they do not clean out the infected nerve inside the tooth. This is why the pain often returns once the tablets are finished, and why a root canal or extraction is usually needed to fix the problem properly.

Understanding this difference makes it easier to see antibiotics as a short term helper, not the main treatment for a root canal infection.

Why the pain often returns after antibiotics

Many patients tell me a similar story: “The antibiotics worked for a few days, then the pain came back again.” This does not mean the medication was “wrong” or that your body failed. It usually means the tablets helped the tissues around the tooth, but the source of the infection inside the tooth was still there.

What happens when the course finishes

While you are taking antibiotics, the bacterial load in the surrounding tissues drops and inflammation settles. When you stop the tablets, there is no longer any medication flowing through your bloodstream to support that area.

Because the infected nerve space inside the tooth was never cleaned out, the bacteria there can start to multiply again. As pressure builds, you may notice:

  • Throbbing or pulsing pain returning
  • Discomfort when biting on that tooth
  • New tenderness or swelling in the gum
  • Pain waking you at night again

Why repeating antibiotics is not the answer

It can be tempting to ask for another course of antibiotics when this happens, especially if the first one gave some relief. But repeating courses without treating the root cause can:

  • Mask symptoms and delay proper treatment
  • Increase the risk of antibiotic resistance
  • Upset your stomach or general health
  • Allow the underlying infection to gradually worsen
The key message

Antibiotics can buy us time and protect you if there is spreading infection, but they do not replace root canal treatment or extraction. Once pain returns after a course of antibiotics, it is usually a sign that the tooth itself now needs definitive treatment, not more tablets.

If this sounds like your situation, the next step is not another prescription, but a careful exam, X rays and an honest conversation about the best way to treat the tooth itself.

When antibiotics are still helpful and necessary

Although antibiotics cannot clean the inside of an infected nerve, there are situations where they are still very important. The goal in these cases is to protect your overall health while we plan proper dental treatment, not to avoid treatment altogether.

Situations where I am more likely to prescribe antibiotics

In my own practice, I consider antibiotics when I see one or more of the following:

  • Spreading swelling – the infection is moving into the face, cheek or under the jaw, not just a small local area on the gum.
  • Fever or feeling unwell – signs that your body is fighting a stronger infection.
  • Difficulty swallowing or opening your mouth – these can be urgent warning signs that need prompt attention.
  • Medically vulnerable patients – for example, certain heart conditions, reduced immunity or complex medical histories where infection control is more critical.
  • Emergency pain where immediate treatment is not yet possible – antibiotics may offer support while we arrange the earliest appointment to treat the tooth properly.

Antibiotics as part of a bigger plan, not instead of one

In all of these situations, antibiotics are used alongside a clear plan to address the tooth itself, not as a replacement for that plan. This may mean scheduling:

  • Root canal treatment to clean and seal the inside of the tooth
  • Extraction when the tooth cannot be saved reliably
  • Drainage of an abscess if needed to relieve pressure
What this means for you

If I prescribe antibiotics for a tooth infection, it is because I believe they are needed for your general health or to support you safely until we can treat the tooth. I will always pair this with a conversation about the next step, so you are not left relying on repeated courses of medication that cannot fix the source of the problem.

The most important question is not “Can I have more antibiotics”, but “What is the best way to treat this tooth so the infection does not keep coming back”.

What actually treats a root canal infection

Once the nerve inside a tooth is badly inflamed or has died, tablets on their own cannot clean that space. The infection is sitting inside tiny canals that no longer have a healthy blood supply. To fix the problem properly, we need to either clean and seal those canals or remove the tooth altogether.

Option 1 - root canal treatment

Root canal treatment is a way of keeping your own tooth while removing the infected or dying nerve tissue inside it. In simple terms, this involves:

  • Creating a small opening in the tooth to reach the nerve space
  • Gently removing inflamed or dead tissue from inside the canals
  • Disinfecting and shaping the canals so they can be filled
  • Sealing the canals with a root filling material
  • Protecting the tooth with a strong filling or crown

When this is done well and the tooth is properly restored on top, it often becomes a quiet, reliable part of your bite again.

Option 2 - removing the tooth

In some situations, the kinder option is to remove the tooth. This might be the case if:

  • The tooth is cracked down the root
  • There is not enough strong tooth left to hold a crown
  • There is severe bone loss or advanced gum disease around the tooth
  • The tooth has already had complex treatment that has not worked

After removal, we can talk about options to replace the tooth, such as an implant, bridge or partial denture, depending on your goals and budget.

The simple way I put it

Antibiotics can help calm the outside of the tooth. Root canal treatment or extraction is what actually deals with the inside. The long term solution is always about treating the source, not just quietening the symptoms.

During your visit, I will go through both paths with you, explain the likely outlook for your tooth and help you choose the option that feels right for your mouth and your life.

When to seek urgent dental care

If you are relying on antibiotics or if your pain keeps returning, it is time to be seen as soon as possible. Root canal infections do not disappear on their own and delaying treatment can make the final outcome more complicated or more costly.

You should contact us urgently if you notice any of the following:

  • Swelling in the face, cheek, jaw or under the tongue
  • Fever, chills or feeling unwell
  • Difficulty swallowing or opening your mouth
  • Pain waking you at night repeatedly
  • A bad taste or discharge coming from the gum
  • Pain returning soon after finishing antibiotics
My reassurance

You do not need to wait until things become severe. Most root canal problems can be treated comfortably and calmly when addressed early. Whether it is a simple X-ray or a full treatment plan, we are here to guide you through each step with clarity and care.

We offer same day emergency appointments and will always prioritise you if your symptoms are worsening or not settling with medication.

Still feeling pain after antibiotics?

You are not alone and you are not doing anything wrong. We can assess the tooth, explain why the pain keeps returning and guide you through the gentlest, most effective treatment options.

Book an Appointment